Custom Synthesis of Standard and Challenging Modified Peptides
BioGenes’ range of services includes epitope prediction and peptide design as well as custom synthesis of standard and challenging modified peptides.
The synthesis service will be performed with Biosyntan GmbH, our long-term partner with excellent expertise in synthesis of linear and cyclic peptides.
Our service includes:
Peptide design
Starting with a protein sequence, we support you in choosing the suitable peptide for producing antibodies
Automated, multiple solid-phase peptide synthesis
Chain length up to 100 residues in a scale of 1 to 500 mg,
Purification by preparative HPLC (standard purity: 80% or 95%)
Analysis of all products by HPLC and mass spectrometry
Synthesis and modification of peptides
Modified peptides, e. g. phosphorylation, glycosylation
Fluorescently labeled peptides, e.g. Rhodamine 110 (Rh110) protease substrates
Histone and cell-penetrating peptides
N-and C-terminal derivatisation, biotinylation
Peptide thioesters for chemical ligation
Conjugation of peptides to proteins
Fluorescence labeling
Single isomer DYOMICS label (spectral range 400 – 800 nm)
FRET-systems
Protease substrates (caspases, beta-secretase, and others):
with AMC or AFC, or with Rh110
symmetric: (peptide)2-Rh110 or
asymmetric: peptide-Rh110-X (X = D-Pro or gamma-Glu)
NEW: Fluorescently labeled ubiquitin derivatives (purity: 95% (HPLC), chemically synthesised), e.g. Ubiquitin(1-76)-Rh110-D-Pro or Ubiquitin(1-76)-AMC