Specialist for Sophisticated Antibody Development
Specialist for Sophisticated Antibody Development

Modification of Antibodies

  • F(ab) and F(ab)fragmentation to be used e.g. for monoclonal anti-ID development
    • Test cleavage of a low amount of antibody using Papain and Pepsin to determine the best cleavage conditions
  • Large-scale cleavage (up to 100 mg antibody) using the selected enzyme incl. quality control
  • Conjugation with peroxidase and alkaline phosphatase
  • Labeling with fluorescent dyes 
  • Biotinylation 
  • Gold labeling: production of colloid conjugates with defined particle size
  • Conjugation with latex or magnetic beads (defined particle sizes) 
  • Coating of a carrier with antibodies (columns, plates, tubes etc.)